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As a PhD student at St. John's College, University of Cambridge, Tanushree delves into the intricate world of biophysical chemistry, focusing on exploring the physicochemical determinants of phase transitions in complex multicomponent biomolecular condensates. These dynamic assemblies, often referred to as 'membrane-less organelles,' emerge through liquid-liquid phase separation, exerting profound influence over a myriad of biological processes. Tanushree explores how the mis regulation of these condensates contributes to a spectrum of neurodegenerative disorders, including Alzheimer’s, Parkinson’s, and Amyotrophic Lateral Sclerosis, underscoring the pivotal role they play in cellular organization, both in health and disease.
Under the expert guidance of Professor Tuomas Knowles and Dr. Jonathan Nixon Abell, she strives to uncover the fundamental principles governing the behaviour of these biomolecular condensates, aiming to shed light on their potential as therapeutic targets for combating devastating neurological conditions.
Beyond the laboratory, Tanushree's passion extends to the realm of public policy. She is deeply intrigued by the intersection of science, engineering, and policymaking, recognizing the profound impact that informed policy decisions can have on the advancement of society. Tanushree aspires to contribute her scientific expertise to inform evidence-based policymaking, fostering innovation and sustainable development for the betterment of the nation and beyond.